*Prion biology and diseases / Edited by Stanley B. Prusiner. – 2. ed. – Cold spring harbor (N.Y.) : Cold spring harbor laboratory press, c2004. – XIII, 1050 p. : ill. ; 24 cm.
Prion proteins are a unique form of infectious pathogen responsible for bovine spongiform encephalopathy (mad cow disease), humans’ Creutzfeldt-Jakob disease, and other emerging diseases. Hoping to attract younger scientists to the field of prion biology, Prusiner (U. of California at San Francisco) presents the new edition of this text. The first six chapters serve as a basic introduction to prion biology, examining the development of the prion concept, bioassays of prions, transmission and replication, and structural issues. The remaining 12 papers describe specific prions and prion diseases in fungi, animals and humans; discuss issues of transgenetics and cell biology; and explore biosafety and therapeutics.